COVID-19 Vaccines 2024-25 (United States)
The first chart below provides dosing and storage information for COVID-19 vaccines approved or authorized in the US. Links to the prescribing information and fact sheets (EUA) for healthcare professionals and the patient package insert are provided in footnote a. A second chart provides information and resources to help you address frequently asked questions about COVID-19 vaccination.
--Information in this chart is from the US product information (prescribing information or fact sheet) cited in footnote a, unless otherwise cited.--
Vaccine |
Dosing |
Storage/Stability |
Comirnaty (COVID-19 vaccine, mRNA) 2024 to 2025 formula (Omicron KP.2) for patients ≥12 years of age. Pfizer-BioNTech |
For patients ≥12 years of age:
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Pfizer-BioNTech COVID-19 vaccine, mRNA. 2024 to 2025 formula (Omicron KP.2) for patients 5 years through 11 years of age. Emergency Use Authorization BLUE cap and label border. |
For patients 5 years through 11 years of age.
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Pfizer-BioNTech COVID-19 vaccine, mRNA. 2024 to 2025 formula (Omicron KP.2) for patients 6 months through 4 years of age Emergency Use Authorization YELLOW cap and label border |
For patients 6 months through 4 years of age.
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Spikevax COVID-19 vaccine, mRNA. 2024 to 2025 formula (Omicron KP.2) for patients ≥12 years of age. Moderna |
For patients ≥12 years of age.
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Moderna COVID-19 vaccine, mRNA. 2024 to 2025 formula (Omicron KP.2) for patients 6 months to 11 years of age Emergency Use Authorization |
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Abbreviations: EUA = Emergency Use Authorization; IM = intramuscular
- US prescribing information or fact sheet (for vaccines with EUA) used in creation of this chart, and corresponding patient package inserts for recipient/caregiver:
- Comirnaty for patients ≥12 years of age (August 2024): https://www.fda.gov/media/151707/download?attachment. (Includes information for recipients/caregivers).
- Pfizer COVID-19 vaccine for patients 6 months through 11 years of age (August 2024): https://www.fda.gov/media/167211/download?attachment.
- Fact sheet for recipients/caregivers: https://www.fda.gov/media/167212/download?attachment.
- Spikevax for patients ≥12 years of age (August 2024): https://www.fda.gov/media/155675/download?attachment.
- Patient package insert: https://www.fda.gov/media/155762/download?attachment.
- Moderna COVID-19 vaccine for patients 6 months through 11 years (August 2024): https://www.fda.gov/media/167208/download?attachment.
- Fact sheet for recipients/caregivers: https://www.fda.gov/media/167209/download?attachment.
- Immunocompromise = solid organ transplant patients or similar level of immunocompromise. For a full list of CDC-recommended conditions and vaccination recommendations, see CDC guidance at: https://www.cdc.gov/vaccines/covid-19/clinical-considerations/covid-19-vaccines-us.html.
---Continue to the next section for a chart, “Frequently Asked Questions About COVID-19 Vaccination.”---
Frequently asked questions about COVID-19 vaccination
Question |
Pertinent information or Suggested Resources |
How do COVID-19 vaccines work? |
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Do mRNA vaccines affect DNA? |
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Can a COVID-19 vaccine cause a COVID-19 infection? |
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Can a patient get a COVID-19 vaccine if they have a COVID infection? |
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How effective are COVID-19 vaccines? |
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Can COVID-19 vaccines be given with other vaccines? |
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What are some common adverse effects of COVID-19 vaccines, and what can be done about them? |
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Do COVID-19 vaccines cause heart problems? |
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Do COVID-19 vaccines cause Bell’s palsy? |
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Can COVID-19 vaccines cause ischemic stroke? |
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Do COVID-19 vaccines cause Guillain-Barre syndrome? |
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Will COVID-19 vaccination cause a positive COVID test? |
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Can antibody testing be used to assess the need for COVID-19 vaccination? |
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Do patients need to stick with the same vaccine every year? |
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What dose should a child receive if they transition from a younger to older age group between doses in a series? |
If immunocompromised:
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Do COVD-19 vaccines prevent “long COVID”? |
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Can patients who are pregnant or breastfeeding get a COVID vaccine? |
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References
- CDC. Long COVID basics. https://www.cdc.gov/covid/long-term-effects/index.html. (Accessed August 26, 2024).
- Trinh NT, Jödicke AM, Català M, et al. Effectiveness of COVID-19 vaccines to prevent long COVID: data from Norway. Lancet Respir Med. 2024 May;12(5):e33-e34.
- Al-Aly Z, Davis H, McCorkell L, et al. Long COVID science, research and policy. Nat Med. 2024 Aug;30(8):2148-2164.
- CDC. COVID-19 vaccine frequently asked questions. https://www.cdc.gov/covid/vaccines/faq.html. (Accessed August 26, 2024).
- CDC. Myths and Facts About COVID-19 Vaccines. https://www.cdc.gov/covid/vaccines/myths-facts.html. (Accessed August 26, 2024).
- Fairweather D, Beetler DJ, Di Florio DN, et al. COVID-19, Myocarditis and Pericarditis. Circ Res. 2023 May 12;132(10):1302-1319.
- Buoninfante A, Andeweg A, Genov G, Cavaleri M. Myocarditis associated with COVID-19 vaccination. NPJ Vaccines. 2024 Jun 28;9(1):122.
- CDC. Interim clinical considerations for use of COVID-19 vaccines in the United States. Last reviewed August 23, 2024. https://www.cdc.gov/vaccines/covid-19/clinical-considerations/interim-considerations-us.html#Interchangeability. (Accessed August 27, 2024).
- Wallace M, Moulia D, Blain AE, et al. The Advisory Committee on Immunization Practices' Recommendation for Use of Moderna COVID-19 Vaccine in Adults Aged ≥18 Years and Considerations for Extended Intervals for Administration of Primary Series Doses of mRNA COVID-19 Vaccines - United States, February 2022. MMWR Morb Mortal Wkly Rep. 2022 Mar 18;71(11):416-421.
- CDC. Getting your COVID-19 vaccine. https://www.cdc.gov/covid/vaccines/getting-your-covid-19-vaccine.html. (Accessed August 27, 2024).
- CDC. Selected adverse events reported after COVID-19 vaccination. Updated September 12, 2023. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/adverse-events.html. (Accessed August 27, 2024).
- CDC. CDC’s state of vaccine confidence insights report. August 21, 2023. https://www.cdc.gov/vaccines/covid-19/downloads/sovc-quarter-1-2023.pdf. (Accessed August 27, 2024).
- Forshee R. Advisory Committee on immunization Practices. Update on original COVID-19 vaccine and COVID-19 vaccine, bivalent safety. February 24, 2023. https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2023-02/slides-02-24/covid-03-forshee-508.pdf. (Accessed August 27, 2024).
- Boehmer TK, Kompaniyets L, Lavery AM, et al. Association Between COVID-19 and Myocarditis Using Hospital-Based Administrative Data - United States, March 2020-January 2021. MMWR Morb Mortal Wkly Rep. 2021 Sep 3;70(35):1228-1232.
- CDC. Benefits of getting vaccinated. https://www.cdc.gov/covid/vaccines/benefits.html?CDC_AAref_Val=https://www.cdc.gov/coronavirus/2019-ncov/vaccines/vaccine-benefits.html. (Accessed August 27, 2024).
Cite this document as follows: Clinical Resource, COVID-19 Vaccines 2024-2025 (United States). Pharmacist’s Letter/Pharmacy Technician’s Letter/Prescriber Insights. August 2024. [400863]