patients on Allegra who say it doesn't work

June 2001

Do you have patients on Allegra who say it doesn't work? Do they take it with fruit juice?

Preliminary evidence suggests that bioavailability of Allegra is almost 70% less when taken with apple, grapefruit, or orange juice.

This is completely different than the grapefruit juice interaction with cytochrome P450 enzymes.

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