drug interaction alerts for Plavix (clopidogrel)

January 2010

You'll see more drug interaction alerts for Plavix (clopidogrel).

We've gotten used to the uptick in warnings against combining Plavix and omeprazole. Omeprazole blocks the "CYP 2C19" enzyme that converts Plavix to its active form...so Plavix may not work as well.

In fact, new evidence shows omeprazole reduces Plavix's anti-blood clotting effects by up to half.

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