Don't Automatically Override Drug Interaction Alerts Involving Domperidone

You'll see stronger warnings with domperidone (Motilium, etc)...now that Health Canada is strengthening label warnings again.

Domperidone labelling already warns about a small increased risk of irregular heart rhythms or sudden cardiac death...especially in patients over age 60 or on doses over 30 mg/day.

But now the list of high-risk patients is growing...and domperidone will be contraindicated in certain patients to improve safety.

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