Keep Risk of Heart Problems With Cholinesterase Inhibitors in Perspective

A new Health Canada warning will spur questions about the risk of heart problems with donepezil, galantamine, or rivastigmine.

About 3 million Rxs for these cholinesterase inhibitors are dispensed in Canada each year...usually for Alzheimer’s or Parkinson’s dementia.

Labelling for these meds already warns about slow heart rate. Now there’ll be warnings about QT prolongation and torsades...which can lead to serious irregular heart rhythms or even sudden death.

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