Tasmar is the first in a new class

    Tasmar is the first in a new class...called COMT inhibitors.

    COMT (catechol-O-methyltransferase) is an enzyme that metabolizes levodopa to an inactive metabolite.

    This is different from the decarboxylase enzyme that's inhibited by carbidopa or benserazide. Decarboxylase metabolizes levodopa to dopamine.

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