Does Vioxx (rofecoxib) cause more cardiovascular problems than other NSAIDs

Does Vioxx (rofecoxib) cause more cardiovascular problems than other NSAIDs?

This has been a long-running debate.

We know that all NSAIDs, including COX-2 inhibitors, can decrease blood flow to the kidneys. This can lead to edema... increased blood pressure...and heart failure.

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