Demystify Gastroprotection With Antithrombotics

There’s still debate about how to limit GI bleeding risk in patients taking blood thinners (aspirin, apixaban, warfarin, etc).

These meds increase GI bleeding risk...especially if more than 1 is needed, such as for patients with atrial fib plus a recent coronary stent. But PPIs (omeprazole, etc) also have risks (C. diff, etc).

In general, patients will need gastroprotection if they’re on a blood thinner with a prior GI bleed...if they also need a chronic steroid or NSAID...or if 2 or more blood thinners are necessary.